Chemical Name |
Vofopitant dihydrochloride |
CAS Number |
168266-51-1 |
MDL Number |
MFCD00947113 |
Molecular Formula |
C21H25Cl2F3N6O |
Molecular Weight |
505.36 |
Synonyms |
GR 205171A |
Introduction of 168266-51-1 :
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent[1]. IC50 & Target: pKi: 9.5 (NK1, rat), 10.6 (NK1, human)[1]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.