CAS No. 163252-36-6, Clevudine


NLT 98%

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Chemical Name Clevudine
CAS Number 163252-36-6
MDL Number MFCD00935785
Molecular Formula C10H13FN2O5
Molecular Weight 260.22
Introduction of 163252-36-6 :

Clevudine is an antiviral drug for the treatment of hepatitis B. Target: HBV Clevudine is a nucleoside analog with an unnatural beta-L configuration. Clevudine showed potent antiviral activity during therapy and induced a sustained posttreatment antiviral effect for 6 months after a 12-week treatment period, and this was associated with a sustained normalization of ALT levels [1]. Clevudine showed a potent antiviral response, and its effect was higher in HBeAg-negative patients, with rapid viral load reduction after therapy. However, long-term therapy for more than 1 year resulted in the development of considerable resistance and myopathy. Therefore, we should consider alternative antiviral agents if clevudine resistance or clevudine-induced myopathy is developed in patients on clevudine for the treatment of CHB [2].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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