CAS No. 162641-16-9, HQL-79


NLT 98%

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Chemical Name HQL-79
CAS Number 162641-16-9
MDL Number MFCD00936179
Molecular Formula C22H27N5O
Molecular Weight 377.48
Introduction of 162641-16-9 :

HQL-79 is a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS[1]. IC50 & Target: IC50: 6 μM (H-PGDS)[1]
Kd: 0.8 μM (H-PGDS)[1] In Vitro: HQL-79 is a competitive inhibitor against substrate PGH2 and a non-competitive one against GSH[1].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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