GSK591
| Chemical Name | GSK591 |
|---|---|
| CAS Number | 1616391-87-7 |
| Molecular Formula | C22H28N4O2 |
| Molecular Weight | 380.48 |
| Synonyms | EPZ015866;GSK3203591 |
Introduction of 1616391-87-7 :
GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM[1]. IC50 & Target: IC50: 4 nM (PRMT5)[1] In Vitro: GSK591 (5 μM; MCF7, T47D, and MCF10A cells) treatment suppresses breast cancer stem cells (BCSCs) proliferation and self-renewal. GSK591 reduces BCSCs numbers in vitro[2].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.