[Des-Arg9]-Bradykinin is a Bradykinin (B₁) receptor agonist that displays selectivity for B₁ over B₂ receptors. IC50 & Target: Bradykinin (B₁) receptor^[1] In Vitro: The B₂ receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B₁ receptor mediates the action of [Des-Arg⁹]-Bradykinin (des-Arg⁹-BK) and Lys-des-Arg Arg⁹-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively^[1].