Chemical Name |
Tropodifene |
CAS Number |
15790-02-0 |
MDL Number |
MFCD00869003 |
Molecular Formula |
C25H29NO4 |
Molecular Weight |
407.50 |
Synonyms |
Tropaphen |
Introduction of 15790-02-0 :
Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor. IC50 & Target: α-Adrenergic[1] In Vivo: Tropaphen has a beneficial effect on hypertension. The therapeutic effect of this preparation is more constant in diseases accompanied by spasm of the peripheral vessels. Tropaphen has a very marked adrenolytic and vasodilator action. It greatly lowers the tone of the peripheral vessels. The preparation is effective starting with a dose of 0.1 mg/kg. After injection of the drug in a dose of 0.25 mg/kg, a considerable and gradually progressive decrease in the perfusion pressure takes place. The pressure falls by 30-35% and remained at a low level for 90-100 min. With a dose of tropaphen of 0.5 mg/kg, the perfusion pressure falls by 40-45% and remains low for 120 min or more. Strong vasodilatation is also observed after injection of tropaphen into intact rabbits[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.