Plevitrexed
| Chemical Name | Plevitrexed |
|---|---|
| CAS Number | 153537-73-6 |
| MDL Number | MFCD09837719 |
| Molecular Formula | C26H25FN8O4 |
| Molecular Weight | 532.53 |
| Synonyms | ZD 9331;BGC9331 |
Introduction of 153537-73-6 :
Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical[1][2][3]. In Vitro: ZD9331 inhibits the transport of [3H]-methotrexate into L1210 and W1L2 cells with a Ki of∼1 µM[3].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.