Chemical Name |
Fmoc-Lys(Dde)-OH |
CAS Number |
150629-67-7 |
MDL Number |
MFCD00278818 |
Molecular Formula |
C31H36N2O6 |
Molecular Weight |
532.63 |
The Nε-protecting group Dde is orthogonal to both Fmoc and Boc which allows on-resin modification of lysine side chains during Fmoc/tBu-based SPPS. The applications of Dde side-chain protection include synthesis of branched or di-epitopic peptides, preparation of MAP core molecules and lipo-MAPS, the synthesis of cyclic peptides, TASP molecules, and templates for combinatorial chemistry and synthetic proteins. Dde can be cleaved by 2% hydrazine in DMF.
Purity |
NLT 98% |
Storage |
-20 ± 5 ºC |
*The above information is for reference only.