Loviride
| Chemical Name | Loviride |
|---|---|
| CAS Number | 147362-57-0 |
| MDL Number | MFCD00867484 |
| Molecular Formula | C17H16Cl2N2O2 |
| Molecular Weight | 351.23 |
| Synonyms | R 89439 |
Introduction of 147362-57-0 :
Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1]. IC50 & Target: IC50: 0.3 µM (Reverse transcriptase)[1] In Vitro: Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.