GR 113808
| Chemical Name | GR 113808 |
|---|---|
| CAS Number | 144625-51-4 |
| MDL Number | MFCD00912901 |
| Molecular Formula | C19H27N3O4S |
| Molecular Weight | 393.50 |
Introduction of 144625-51-4 :
GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors[1]. In Vivo: GR113808 (intraperitoneal injection; 1 mg/kg; 5-7 days starting 24 h after induction of colitis) shows a significant increase in the disease activity index (DAI),which includes evaluation of weight loss, stool consistency, and presence of fecal blood[2].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.