Chemical Name |
Fmoc-Asp-allyl ester |
CAS Number |
144120-53-6 |
MDL Number |
MFCD00190874 |
Molecular Formula |
C22H21NO6 |
Molecular Weight |
395.41 |
Synonyms |
Fmoc-Asp-OAll |
α-Allyl esters are useful tools for the on-resin head-to-tail cyclization of peptides and for the synthesis of side-chain lactam peptides, glyco- and sulfo-peptides, and branched peptides. Allyl esters are cleaved under mild conditions using Pd(0). These conditions are compatible with Fmoc- and Boc-SPPS.
The Asp α-Allyl esters show a somewhat higher propensity for base-catalyzed aspartimide formation than the corresponding β-esters.
Fmoc-Asp-OAll is a versatile educt for synthesizing complex Asp and Asn derivatives, e.g., N-glycosylated Asn building blocks.
Purity |
NLT 98% |
Storage |
-20 ± 5 ºC |
*The above information is for reference only.