Chemical Name |
BAN ORL 24 |
CAS Number |
1401463-54-4 |
MDL Number |
MFCD21607098 |
Molecular Formula |
C27H35N3O2 |
Molecular Weight |
433.59 |
Introduction of 1401463-54-4 :
BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). IC50 value: 0.27 nM Target: NOP receptor BAN ORL 24 inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.