Chemical Name |
A 1070722 |
CAS Number |
1384424-80-9 |
MDL Number |
MFCD22580422 |
Molecular Formula |
C17H13F3N4O2 |
Molecular Weight |
362.31 |
Introduction of 1384424-80-9 :
A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain[1]. IC50 & Target: Ki: 0.6 nM (GSK-3)[1]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.