CAS No. 138147-78-1, RC-3095


NLT 98%

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Chemical Name RC-3095
CAS Number 138147-78-1
MDL Number MFCD07366644
Molecular Formula C58H80F3N15O11
Molecular Weight 1220.34
Introduction of 138147-78-1 :

RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2]. IC50 & Target: Bombesin receptor; GRPR[1] In Vivo: RC-3095 impairs aversive but not recognition memory in Wistar male rats[1].
RC-3095 (0.3 mg/kg or 1 mg/kg; S.C.) shows anti-inflammatory effects in 2 experimental models of arthritis, collagen-induced arthritis (CIA) and antigen-induced arthritis (AIA)[2].
Arthritic mice treated with RC-3095 show a significant reduction in the concentrations of IL-17, IL-1 , and TNF, and showed a diminished expression of GRPR[2].

Purity NLT 98%
Storage at 20ºC 2 years
*The above information is for reference only.

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