RC-3095
| Chemical Name | RC-3095 |
|---|---|
| CAS Number | 138147-78-1 |
| MDL Number | MFCD07366644 |
| Molecular Formula | C58H80F3N15O11 |
| Molecular Weight | 1220.34 |
Introduction of 138147-78-1 :
RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2]. IC50 & Target: Bombesin receptor; GRPR[1] In Vivo: RC-3095 impairs aversive but not recognition memory in Wistar male rats[1].
RC-3095 (0.3 mg/kg or 1 mg/kg; S.C.) shows anti-inflammatory effects in 2 experimental models of arthritis, collagen-induced arthritis (CIA) and antigen-induced arthritis (AIA)[2].
Arthritic mice treated with RC-3095 show a significant reduction in the concentrations of IL-17, IL-1 , and TNF, and showed a diminished expression of GRPR[2].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.