BQ-123
| Chemical Name | BQ-123 |
|---|---|
| CAS Number | 136553-81-6 |
| MDL Number | MFCD00905129 |
| Molecular Formula | C31H41N6NaO7 |
| Molecular Weight | 632.68 |
Introduction of 136553-81-6 :
BQ-123 is a selective endothelin A receptors (ETAR) antagonist with an IC50 value of 7.3 nM and a Ki vaule of 25 nM[1][2]. IC50 & Target: IC50: 7.3 nM (Endothelin A receptors)[1]
Ki: 25 nM (Endothelin A receptors)[2] In Vivo: BQ-123 (3 mg/kg; i.v.; given 15 minutes before pentylenetetrazole (PTZ)) impedes the formation and spread of seizure to a great degree in PTZ (50 mg/kg; i.p.) +BQ-123 groups[3].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.