E3330
| Chemical Name | E3330 |
|---|---|
| CAS Number | 136164-66-4 |
| MDL Number | MFCD00901331 |
| Molecular Formula | C21H30O6 |
| Molecular Weight | 378.46 |
| Synonyms | APX-3330 |
Introduction of 136164-66-4 :
E3330 (APX-3330) is a direct, orally active AP endonuclease 1 (APE1; also known as REF-1) inhibitor, which suppresses NF-κB DNA-binding activity. E3330 (APX-3330) blocks TNF-α-induced activation of IL-8 production in liver cancer cell lines. E3330 (APX-3330) shows anticancer properties, such as inhibition of cancer cell growth and migration[1-4]. IC50 & Target: DNA Synthesis, APE1[1-4]
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.