| Chemical Name |
Angiotensin III, human, mouse |
| CAS Number |
13602-53-4 |
| MDL Number |
MFCD00167500 |
| Molecular Formula |
C46H66N12O9 |
| Molecular Weight |
931.09 |
Introduction of 13602-53-4 :
Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively. IC50 & Target: IC50: 0.648 nM (AT2R), 21.1 nM (AT1R)[1] In Vitro: Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively[1]. In Vivo: Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats[3].
| Purity |
NLT 98% |
| Storage |
at 20ºC 2 years |
*The above information is for reference only.
