8-M-PDOT
| Chemical Name | 8-M-PDOT |
|---|---|
| CAS Number | 134865-70-6 |
| MDL Number | MFCD00901636 |
| Molecular Formula | C14H19NO2 |
| Molecular Weight | 233.31 |
| Synonyms | AH-002 |
Introduction of 134865-70-6 :
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity[1][2]. IC50 & Target: pKi: 8.23 (Melatonin MT2 receptor) and 8.95 (Melatonin MT1 receptor)[2] In Vivo: 8-M-PDOT (10 µg/µL; administrated into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) treatment shows anxiolytic-like effect[2].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.