Tolcapone
| Chemical Name | Tolcapone |
|---|---|
| CAS Number | 134308-13-7 |
| MDL Number | MFCD00866569 |
| Molecular Formula | C14H11NO5 |
| Molecular Weight | 273.24 |
| Synonyms | Ro 40-7592 |
Introduction of 134308-13-7 :
Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis and protect against extracellular toxicity induced by the aggregation of both proteins in PC12 cells[1][2]. IC50 & Target: COMT[1]
α-syn and Aβ42 oligomerization, fibrillogenesis[2]
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.