Nicotinamide riboside
| Chemical Name | Nicotinamide riboside |
|---|---|
| CAS Number | 1341-23-7 |
| MDL Number | MFCD16621007 |
| Molecular Formula | C11H15N2O5 |
| Molecular Weight | 255.25 |
Introduction of 1341-23-7 :
Nicotinamide riboside is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside is used in dietary supplements[1]. IC50 & Target: NAD[+], SIRT1 and SIRT3[1] In Vitro: Nicotinamide riboside (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. In Vivo: Chronic Nicotinamide riboside (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD[+] content in a tissue-specific manner[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.