Chemical Name |
Odapipam |
CAS Number |
131796-63-9 |
MDL Number |
MFCD00868632 |
Molecular Formula |
C19H20ClNO2 |
Molecular Weight |
329.82 |
Synonyms |
NNC 756 |
Introduction of 131796-63-9 :
Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer[1][2]. IC50 & Target: Dopamine D1 receptor[1] In Vivo: The metabolism of Odapipam has been studied with phenobarbital-induced rat liver microsomes. During the incubation of Odapipam, five different metabolites are formed. The electron-ionization (EI+) mass spectra of the metabolites indicated the formation of N-desmethyl-Odapipam, 1-hydroxy-Odapipam, the two isomers of 3′-hydroxy-Odapipam and a metabolite which is dehydrogenated in the dihydrobenzofuran moiety[3].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.