Chemical Name |
E-6123 |
CAS Number |
131614-02-3 |
MDL Number |
MFCD00869970 |
Molecular Formula |
C23H22ClN5OS |
Molecular Weight |
451.97 |
Introduction of 131614-02-3 :
E-6123 is a platelet-activating factor (PAF) receptor antagonist. IC50 & Target: PAF[1] In Vitro: E-6123 (E6123) partially inhibits the Thapsigargin-induced increase in the levels of interleukin-6 mRNA and interleukin-6 protein. To clarify the role of the concurrently produced cell-associated PAF in the thapsigargin-induced increase in the interleukin-6 mRNA level and interleukin-6 production, the effects of the PAF receptor antagonist E-6123 are examined. E-6123 at 1 and 10 μM partially inhibits the Thapsigargin (46.1 nM)-induced increase in the interleukin-6 mRNA level at 4 h and interleukin-6 production at 8 h[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.