TAK1/MAP4K2 inhibitor 1
| Chemical Name | TAK1/MAP4K2 inhibitor 1 |
|---|---|
| CAS Number | 1315330-11-0 |
| MDL Number | MFCD22572824 |
| Molecular Formula | C29H31F3N6O2 |
| Molecular Weight | 552.59 |
Introduction of 1315330-11-0 :
TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41.1 nM and 18.2 nM, respectively. In Vivo: TAK1/MAP4K2 inhibitor 1 has moderate terminal elimination half-life (t1/2=2.94 h for mice (1 mg/kg, iv))[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.