Chemical Name |
Duocarmycin SA |
CAS Number |
130288-24-3 |
MDL Number |
MFCD01939574 |
Molecular Formula |
C25H23N3O7 |
Molecular Weight |
477.47 |
Introduction of 130288-24-3 :
Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM[1]. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.