Levocetirizine (dihydrochloride)
| Chemical Name | Levocetirizine (dihydrochloride) |
|---|---|
| CAS Number | 130018-87-0 |
| MDL Number | MFCD04112703 |
| Molecular Formula | C21H25ClN2O3 |
| Molecular Weight | 388.89 |
| Synonyms | (R)-Cetirizine (dihydrochloride) |
Introduction of 130018-87-0 :
Levocetirizine dihydrochloride ((R)-Cetirizine dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Levocetirizine dihydrochloride is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine dihydrochloride has a higher affinity for the histamine H1-receptor than (S)-Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[1]. In Vivo: Levocetirizine (0.4 mg/kg; oral administration; male Sprague-Dawley rats) treatment shows that the Cmax, AUC0-t , AUC0-∞ and t1/2 are 0.34 μg/mL, 3.26 μg h/mL, 3.67 μg h/mL and 2.34 hours, respectively in Sprague-Dawley rats[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.