Chemical Name |
Bis-PEG9-acid |
CAS Number |
1268488-70-5 |
MDL Number |
MFCD11041130 |
Molecular Formula |
C22H42O13 |
Molecular Weight |
514.56 |
Introduction of 1268488-70-5 :
Bis-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.