Chemical Name |
Penitrem A |
CAS Number |
12627-35-9 |
MDL Number |
MFCD00083465 |
Molecular Formula |
C37H44ClNO6 |
Molecular Weight |
634.20 |
Introduction of 12627-35-9 :
Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2]. IC50 & Target: BK channel[1]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.