KS176
1253452-78-6
DY514470
C22H19N3O5
405.40
N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide
| Chemical Name | KS176 |
|---|---|
| CAS Number | 1253452-78-6 |
| MDL Number | MFCD22666402 |
| Molecular Formula | C22H19N3O5 |
| Molecular Weight | 405.40 |
| Synonyms | N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide |
Introduction of 1253452-78-6 :
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1. IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay). Target: BCRP The more detailed information please refer to Compound 9 in the reference.
| Purity | NLT 98% |
|---|---|
| Boiling Point | 510.1±50.0 ºC(Predicted) |
| Storage | at 20ºC 2 years |
*The above information is for reference only.