Thalidomide D4
| Chemical Name | Thalidomide D4 |
|---|---|
| CAS Number | 1219177-18-0 |
| MDL Number | MFCD08063619 |
| Molecular Formula | C13H10N2O4 |
| Molecular Weight | 262.25 |
Introduction of 1219177-18-0 :
Thalidomide D4 is a deuterium labeled Thalidomide. Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2]. IC50 & Target: Kd: ~250 nM (CRL4CRBN)[1]
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.