Cefprozil monohydrate (Cefzil) is a second-generation cephalosporin type antibiotic. Target: Antibacterial Cefprozil , sometimes spelled cefproxil and marketed under the trade name Cefzil, is a second-generation cephalosporin type antibiotic. In Europe it is marketed using the trade names Procef and Cronocef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension. From Wikipedia.