Chemical Name |
Eliprodil |
CAS Number |
119431-25-3 |
MDL Number |
MFCD00866651 |
Molecular Formula |
C20H23ClFNO |
Molecular Weight |
347.85 |
Synonyms |
SL-820715 |
Introduction of 119431-25-3 :
Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). IC50 value: Target: NR2B-NMDA antagonist Human N-type Ca2+ channel currents were inhibited by ifenprodil and eliprodil with IC50 values of 50 microM and 10 microM respectively whereas P-type Ca2+ channel currents were inhibited reversibly by ifenprodil and eliprodil with approximate IC50 values of 60 microM and 9 microM respectively. eliprodil (1 microm) produced a moderate reverse rate-dependent prolongation of the action potential duration (7.4+/-1.5, 8.9+/-2.1 and 9.9+/-1.8% at cycle lengths of 300, 1000 and 5000 ms, respectively; n=9).
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.