Chemical Name |
Loureirin A |
CAS Number |
119425-89-7 |
MDL Number |
MFCD10566607 |
Molecular Formula |
C17H18O4 |
Molecular Weight |
286.32 |
Introduction of 119425-89-7 :
Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. IC50 & Target: Akt[1] In Vitro: Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.