Chemical Name |
MTEP (hydrochloride) |
CAS Number |
1186195-60-7 |
MDL Number |
MFCD08458895 |
Molecular Formula |
C11H9ClN2S |
Molecular Weight |
236.72 |
Introduction of 1186195-60-7 :
MTEP hydrochloride is a potent, selective and non-competitive mGlu5 antagonist with an IC50 of 5 nM and a Ki of 16 nM[1]. MTEP hydrochloride produces antiparkinsonian-like effects[2]. IC50 & Target: IC50: 5 nM (mGluR5)[1]
Ki: 16 nM (mGluR5)[1] In Vivo: MTEP hydrochloride (3-5 mg/2 ml/kg; i.p.) inhibits the catalepsy induced (0.5 mg/kg/2 ml; i.p.) by this neuroleptic[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.