Chemical Name |
Duocarmycin A |
CAS Number |
118292-34-5 |
MDL Number |
MFCD00870416 |
Molecular Formula |
C26H25N3O8 |
Molecular Weight |
507.49 |
Introduction of 118292-34-5 :
Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.