Chemical Name |
Mupirocin (calcium hydrate) |
CAS Number |
115074-43-6 |
MDL Number |
MFCD01765964 |
Molecular Formula |
C52H90CaO20 |
Molecular Weight |
1075.34 |
Introduction of 115074-43-6 :
Mupirocin calcium hydrate is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium hydrate apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2]. In Vitro: Mupirocin Calcium Salt shows a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria. Mupirocin Calcium Salt is highly bound (95% bound) to the protein of human serum, and activity was reduced 10- to 20-fold in the presence of human serum[1]. In Vivo: Mupirocin Calcium Salt is well absorbed after oral and parenteral administration but serum antibiotic concentrations were short-lived as a result of extensive degradation to the antibacterially inactive metabolite, monic acid A[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.