UCPH-101
| Chemical Name | UCPH-101 |
|---|---|
| CAS Number | 1118460-77-7 |
| MDL Number | MFCD12913298 |
| Molecular Formula | C27H22N2O3 |
| Molecular Weight | 422.48 |
Introduction of 1118460-77-7 :
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. IC50 & Target: IC50: 0.66 μM (EAAT1)[1] In Vitro: UCPH-101 and UCPH-102 inhibit EAAT1 anion currents in a concentration-dependent manner, with KD values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. A small but significant decrease in the total expression levels of both HA-EAAT1 and HA-GLAST is observed in cells preincubated with 100 μM UCPH-101 (p=0.048)[1].
| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
*The above information is for reference only.