Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities^[1]. In Vitro: Squalane exhibits a huge potential in nutraceutical and pharmaceutical industries. Squalane shows anticancer, antioxidant, drug carrier, detoxifier, skin hydrating, and emollient activities have been reported both in animal models and in vitro environments^[1].