Chemical Name |
Nitromifene |
CAS Number |
10448-84-7 |
MDL Number |
MFCD00865555 |
Molecular Formula |
C27H28N2O4 |
Molecular Weight |
444.52 |
Synonyms |
CI628 |
Introduction of 10448-84-7 :
Nitromifene is an antagonist of estrogen receptor (ER). IC50 & Target: ER[1] In Vitro: Nitromifene is an antagonist of estrogen receptor (ER). At 0.5 μM and 1.0 μM concentrations, Nitromifene inhibits MCF 7 cell proliferation to 70% of that in drug-free controls. At higher concentrations, Nitromifene is clearly more effective than other metabolites. Specifically bound estradiol is displaced from intact MCF 7 cells by Nitromifene. Nitromifene is an effective antagonist of the ability of calmodulin (CM) to activate cyclic nucleotide phosphodiesterase[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.