Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities^[1][2]. Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure^[1]. In Vivo: Shionone (orally administration; 80 mg/kg; 3 days; once daily) shows the trend of enhancing sputum secreting, but has no effect on ammonia-induced cough and reduces xylene-induced ear edema^[1].