Chemical Name |
Leupeptin (hemisulfate) |
CAS Number |
103476-89-7 |
MDL Number |
MFCD00081028 |
Molecular Formula |
C20H38N6O4 |
Molecular Weight |
426.55 |
Introduction of 103476-89-7 :
Leupeptin hemisulfate is a membrane-permeable thiolprotease inhibitor that inhibits Cathepsin B, Cathepsin H and Cathepsin L, and also impairs amphisome-lysosome fusion[1]. Leupeptin hemisulfate also exhibits anti-inflammatory effect[2]. IC50 & Target: Cathepsin[1] In Vivo: Leupeptin (0-36 mg/kg; intraperitoneal injection; for 4 hours; C57BL/6NCrl male mice) is well tolerated by the animals and produces a strong, dose-dependent increase in LC3b-II in both the total tissue extracts and the lysosome and autophagosome-enriched pellet fraction[2].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.