Name: PGS-IN-1
Brand: 001Chemical
SKU: DY502612
Price: 249.0 USD
Availability: InStock
Rating: 97 (26 reviews)

PGS-IN-1

NLT 98%

CAS Number 102271-49-8

Catalog Number DY502612

Molecular Formula C19H26O3

Molecular Weight 302.41

Synonyms KME-4;alpha-(3,5-Di-tert-Butyl-4-hydroxybenzylidene)gamma-butyrolactone

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Chemical Name	PGS-IN-1
CAS Number	102271-49-8
Molecular Formula	C19H26O3
Molecular Weight	302.41
Synonyms	KME-4;alpha-(3,5-Di-tert-Butyl-4-hydroxybenzylidene)gamma-butyrolactone

Introduction of 102271-49-8 :

PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC₅₀ of 0.28 μM; also inhibits 5-lipoxygenase with an IC₅₀ of 1.05 μM. IC50 & Target: IC50: 0.28 μM (PGS), 1.05 μM (5-lipoxygenase)^[1] In Vitro: The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC₅₀=0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC₅₀=1.05 μM)^[1].

Purity	NLT 98%
Storage	at 20ºC 2 years

*The above information is for reference only.