Chemical Name |
ARN2966 |
CAS Number |
102212-26-0 |
Molecular Formula |
C12H12N2O |
Molecular Weight |
200.24 |
Introduction of 102212-26-0 :
ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. IC50 value: Target: Aβ This potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.