Chemical Name |
Pseudoprotodioscin |
CAS Number |
102115-79-7 |
MDL Number |
MFCD04039839 |
Molecular Formula |
C51H82O21 |
Molecular Weight |
1031.18 |
Introduction of 102115-79-7 :
Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides[1]. In Vitro: In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.