Chemical Name |
CARM1-IN-1 |
CAS Number |
1020399-49-8 |
Molecular Formula |
C26H21Br2NO3 |
Molecular Weight |
555.26 |
Introduction of 1020399-49-8 :
CARM1-IN-1 is a potent and specific CARM1(Coactivator-associated arginine methyltransferase 1) inhibitor with IC50 of 8.6 uM; shows very low activity against PRMT1 and SET7(IC50 > 600 uM). IC50 value: 8.6 uM [1] Target: CRAM1 inhibitor in vitro: CARM1-IN-1(Cmp 7g) displayed high and selective CARM1 inhibition, with lower or no activity against a panel of different PRMTs or HKMTs. In human LNCaP cells, 7g showed a significant dose-dependent reduction of the PSA promoter activity.
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.