Chemical Name |
Piceatannol |
CAS Number |
10083-24-6 |
MDL Number |
MFCD00221715 |
Molecular Formula |
C14H12O4 |
Molecular Weight |
244.24 |
Synonyms |
Astringenin;trans-Piceatannol |
Introduction of 10083-24-6 :
Piceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa,L, Ito, IKr, Ca2+ transients and Na+-Ca2+ exchange except IK1. Shows multiple biological activities such as anti-inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-κB. The effect of piceatannol was not restricted to myeloid cells, as TNF-induced NF-κB activation was also suppressed in lymphocyte and epithelial cells. Piceatannol also inhibited NF-κB activated by H2O2, PMA, LPS, okadaic acid, and ceramide. [1]
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.