Chemical Name |
Ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate |
CAS Number |
1005883-72-6 |
Molecular Formula |
C20H20N4O3 |
Molecular Weight |
364.40 |
Introduction of 1005883-72-6 :
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1]. IC50 & Target: IC50: ~0.2 µM (mAQP7), ~0.7 µM (mAQP3), ~1.1 µM (mAQP9)[1] In Vitro: Z433927330 inhibits glycerol permeability, with an IC50 of ~0.6 µM[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.