Chemical Name |
MX69 |
CAS Number |
1005264-47-0 |
Molecular Formula |
C27H26N2O4S |
Molecular Weight |
474.57 |
Introduction of 1005264-47-0 :
MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment. In Vitro: MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro[1]. In Vivo: MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo[1].
Purity |
NLT 98% |
Storage |
at 20ºC 2 years |
*The above information is for reference only.